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In mice, a vaccine that triggers rejection by the immune system, methamphetamine, a drug that causes a strong dependence.
Cannabis smoking through cocaine, drugs create a physical and psychological dependence. There are few effective ways to fight against this addiction, and research in this area explore various avenues. The team of Kim Janda at the Scripps Institute in California, focuses on methamphetamine: thanks to a vaccine, they obtained mice that produce neutralizing antibody drugs.
Methamphetamine is a synthetic drug that is spreading in Europe in recent years: the euphoric properties, sometimes used as a dopant, it triggers a rapid dependence. U.S. chemists have sought to activate the immune system against this molecule, before it enters the brain. They injected mice with a molecule that mimics methamphetamine: it has almost the same shape, but does not trigger the same deleterious effects. Only, this molecule is not marked by the immune system. Therefore, biologists have ascribed a protein auxiliary large. This assembly is then detected by the immune system, which triggers the production of specific antibodies against this particular construction against the party which is the counterpart of methamphetamine. At a subsequent consumption of methamphetamine, these antibodies recognize the molecule, bind to and neutralize.
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CSIC scientists have developed a method to generate varieties of cucurbits (which includes species such as melon, cucumber, watermelon or pumpkins) were resistant to several viral diseases. The method is based on the silencing of a gene characteristic of the plant, so as not to add anything outside their own species, which reduces the chance that has unexpected repercussions.
Prevent a virus from replicating within an organism and prevent its infection is a study strategy in combating diseases especially virulent or for which no vaccine exists, such as HIV. Something similar can be done with plants, in order to obtain varieties resistant to viral diseases for which no treatment.
This is what has made the CSIC researchers at the Centre for Soil Science and Applied Biology Segura (CEBAS). Scientists have developed a method to generate varieties of cucurbits (which includes species such as melon, cucumber, watermelon or pumpkins) were resistant to several viral diseases that affect them.
The method is based on inducing the silencing of a gene in plants that the virus needs to replicate. This gene encodes a protein that the virus uses to their advantage to multiply in the plant cells. Protein is a necessary piece to work the machinery of virus replication: If there because the protein-encoding gene that is silenced, the virus can lead to infection.
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=> The RIKEN announced a collaboration to develop a vaccine allergy
RIKEN and Torii Pharmaceutical Company announced a collaboration to develop a vaccine against allergy to cedar pollen, a condition that affects more than one in five Japanese. The vaccine, discovered by researchers at RIKEN, consists of molecules macrogol, a polymer linked to DNA pollen. He has already demonstrated its effectiveness and its safety in mice. In particular, according to these preliminary tests, it does not seem to be any risk of anaphylactic shock (severe allergic reaction) following administration of the vaccine.
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A team of researchers at the University College Dublin working on a vaccine against sea lice, a parasite attacking the farmed and wild salmon threaten, would have obtained promising results. These researchers work in collaboration with the Marine Institute, Center for Irish research on marine science and McGill University in Canada.
The salmon louse is a parasite clinging salmon, causing damage to its skin and its scales and causing an overall decline in health of fish. Salmon attacked by this parasite grow slower than healthy fish.
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Researchers at the Faculty of Life Sciences, University of Copenhagen is the first to have synthesized all of the protein causes malaria in pregnant women and their unborn children. This protein, called VAR2CSA, enables malaria parasites to accumulate in the placenta, and could be used as the main component of a vaccine to protect pregnant women from malaria. The research team now plans to test the effectiveness of the vaccine on humans. The aim is to vaccinate within 10 years all African women against malaria, to prevent about 200,000 deaths per year.
Every year, approximately 25 million pregnant women in Sub-Saharan Africa are at risk of contracting malaria. Women who were infected with malaria during their first pregnancy are at considerable risk of severe anemia and fetal growth may be impaired. The malaria parasite accumulates in the placenta, which provides children born prematurely and underweight. These women may also die more frequently during pregnancy or during childbirth. Maternal malaria is the cause of death of about 100,000 to 200,000 infants and 10,000 women each year.
“The team of malaria research in 2003 discovered the protein VAR2CSA responsible for setting the malaria parasite in the placenta,” said Professor Ali Salanti. “The goal is to produce a vaccine based on VAR2CSA would stimulate production of antibodies that prevent the establishment of the parasite in the placenta.
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Researchers at the center of public health at Johns Hopkins Bloomberg (Baltimore, USA) have analyzed the worldwide use of vaccines against the bacterium Haemophilus influenzae type B (Hib), responsible for some three million serious illnesses and nearly 400,000 deaths annually, to determine the factors involved in its adoption by a nation.
The policies of neighboring countries influence the decision to adopt the vaccine against the bacteria Haemophilus influenzae type B (Hib). This suggests a new study that shows how the fact that a country meet the criteria for obtaining the support of the Global Alliance for Vaccines and Immunization (GAVI, for its acronym in English) and that neighboring nations to employ or not vaccine, as well as pricing, are factors of influence.
“It’s important to understand what influences national decisions to introduce new health technologies, including vaccines, which can make them save more lives faster”, explains to SINC Jessica Shearer, lead author and researcher at the school Public Health Johns Hopkins Bloomberg.
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The chikungunya virus is transmitted by mosquitoes and infected millions of people in Africa, Asia and the Indian subcontinent. Currently, there is no cure or vaccine against chikungunya and only symptoms are treated. Scientists from the National Institute of Allergy and Infectious Diseases (NIAID) [1] have developed an experimental vaccine against chikungunya virus effective on monkeys and mice. These results revive the possibility of developing a vaccine in humans have recently been published in the journal Nature Medicine.
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An international team, which is part Mariano Esteban, National Center for Biotechnology (CSIC) in Madrid, has made progress in developing a preventive vaccine against HIV. Protection with positive results, and in a phase I clinical trial in humans, the authors see viable aerosol administration.
An international team involving researchers from the National Center for
Biotechnology in Madrid, belonging to the Consejo Superior de Investigaciones CientÃficas (CSIC), has made progress in developing a preventive vaccine against HIV, the virus causing the pandemic of
AIDS. The proposed model, based on vaccinia virus vectors that have been genetically modified, has been tested in macaques and in a phase I clinical trial in humans.
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There are vaccines for many diseases we can suffer. Many others are the focus of researchers around the world, such as AIDS or malaria But what are the effects in our body? How do they work? When the first vaccine was used in history?
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The full Board Interterritorial National Health System (NHS) today approved the basic common content related to training of health professionals for action against gender violence. The Council also discussed the annual report on gender violence 2008. Women between 21 and 50 years are those with the highest risk of dying by violence.
Approved educational content today in the Inter-Territorial Council of the NHS, chaired by the Minister for Health and Social Policy, Trinidad Jimenez, are divided into concepts on gender and inequality and gender violence; impact of violence on women’s health ;
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Cannabis smoking through cocaine, drugs create a physical and psychological dependence. There are few effective ways to fight against this addiction, and research in this area explore various avenues. The team of Kim Janda at the Scripps Institute in California, focuses on methamphetamine: thanks to a vaccine, they obtained mice that produce neutralizing antibody drugs.