Manuel Serrano, Head of the Tumor Suppression of National Cancer Research Center (CNIO), comments in an article published in the journal Nature the latest research on the relationship between cell senescence and cancer. Part of the results was published last month in Nature Cell Biology and another part is published today in Nature. The works are very useful for developing future therapies.
Two recent studies have attempted to sensitize the mechanisms leading to senescence. One such research is published today in the journal Nature and comes from the group led by Pier Paolo Pandolfi (Harvard University, USA). The first investigation, led by Bruno Amati (European Institute of Oncology, Milan) was published last month in Nature Cell Biology and attended also investiogadores Mariano Barbacid and Oscar Fernandez-Capetillo.
Both groups have managed to genetically engineer mice to make them more susceptible to stress and therefore tumor to senescence. Thus they have failed to protect mice without causing cancer, in addition, no adverse side effects.
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Manuel Serrano, Head of the Tumor Suppression of National Cancer Research Center (CNIO), comments in an article published in the journal Nature, the latest research on the relationship between cell senescence and cancer and whose results were published recently. One of the investigations have discussed the participation of researchers and Oscar Mariano Barbacid CNIO FERNENDEZ-Capetillo.
Manuel Serrano explains how you can induce cellular senescence or aging in tumor cells and prevent cancer.
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